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COURSES OFFERED ...
MOLECULAR BIOLOGY.....
MICRO BIOLOGY .....
TISSUE CULTURE .....
BIOINFORMATICS .....
CLINICAL RESEARCH.....
COURSES OFFERED.....
 
 
Courses

The Institute invites applications for Short/Long Term Training Programmes and Projects works from life science graduates and post graduates in the following fields/ areas:

MOLECULAR BIOLOGY:

An insight into the molecules that initiate, control and sustain our life is called the Science of Molecular Biology. From Mendel's observation of how characters were inherited and segregated in the Pea plant to the unraveling of the Genome of man and a number of other organisms; we have traveled a long way. Molecular Biology and its related fields like Cloning and Genetic Recombination have vested with us the power to combine and exploit the genetic potential of many organisms for the benefit of mankind. The present Courses on these Molecules is designed to give a hands on experience to the students in acquainting themselves with the Basic and Advanced techniques in the field.

Basic Techniques: (Duration: 20 Days)
  • Isolation of Genomic DNA from Different Sources
  • Isolation of Plasmid DNA
  • Isolation of RNA
  • Isolation of enzymes
  • SDS-PAGE
  • Characterization of DNA/RNA by agarose Gel Electrophoresis
Advanced Techniques: (Duration: 20 Days)
  • Restriction Digestion
  • PCR
  • Gene Cloning
  • DNA Fingerprinting
  • Genome Analysis
  • Southern Blotting
  • Western Blotting
  • Purification of enzymes
MICRO BIOLOGY:

Microbes today have become an intrinsic part of human progress. They are used industrially in the manufacture of foods, drugs, vaccines, insecticides, enzymes, hormones and other useful biological products. These versatile unicellular organisms can be coaxed to produce just about anything that there is a gene for through Genetic Engineering and have become the forerunners in the Biotechnology revolution of modern age. Following courses at different levels are designed to train students in using the microbes.......

Basic Techniques (Duration: 20 Days)
  • Sterilization Techniques
  • Preparation of Media
  • Isolation of Microorganisms from different Sources
  • Identification and Characterization of industrially important microbes
  • Preservation and Maintenance of Microbial cultures
  • Studies on the Growth Kinetics of Bacteria
  • Antimicrobial Activity tests
Advanced Techniques (Duration: 20 Days)
  • Molecular identification of microorganisms
  • Mutational studies
  • Purification & Characterization of Enzymes from Microorganisms
  • Isolation of Genomic DNA from Microorganisms
  • Isolation of Plasmid DNA from Bacteria
  • Isolation of RNA
  • Restriction Digestion
  • Transformation and Selection of Transformants
  • Chromatography Techniques
Industrial Microbiology (Duration:20Days)
  • Isolation, Identification and Maintenance of Industrially important Microorganisms
  • Single Cell Protein Production from Microorganisms
  • Enzyme production
  • Food & Water quality tests
  • Isolation of secondary metabolites from microorganisms
Microbial Biotechnology (Duration:20Days)
  • Production of Single Cell protein from microorganisms
  • Purification & characterization of enzymes (Amylase, Protease, Xylanase Lipase, Chitinase etc.).
  • Gene cloning
  • Genetic transformation
TISSUE CULTURE:
Plant Tissue Culture
  • Preparation of MS Medium
  • Callus induction from different explants
  • Shoot Induction
  • Root Induction
  • Micro propagation/Multiple shoot induction
  • Genetic Transformation using Agro bacterium
  • Hairy root culture
  • immobilization of Cells
Bio-pesticides Production & Formulation
  • Biopesticide Production from biocontrol agents.
  • Isolation, Production, Preparation/formulation of Bio-pesticides from agriculturally important microorganisms.
  • Production/formulation of Bio-pesticide from Pseudomonas fluorescence.
  • Production/formulation of Bio-pesticide from Trichoderma viride.
Bio-fertilizers Production & Formulation
  • Production and formulation of Biofertilizers from microorganisms (Azatobacter, Rhizobium, Algae).
BIOINFORMATICS:

During the past many years, the Genome of several organisms, including man have been completely or partially sequenced. However these billions of DNA bases do not tell us much about what all these genes do and their exact role in the process of development, growth, ageing and diseases. We know that ultimately proteins are coded by genes and control the life Processes. However elucidations of the functions of proteins are not yet clear. This is where functional genomics, proteomics and bioinformatics are expected to play a major role. Bioinformatics is an amalgamation of the data in biological sciences and tools of computing in information technology. Bioinformatics uses computational power to catalogue, organize and structure these complex databases and pieces them into meaningful biological entities to provide easy access to the data on many developments in the fields of Medical, Pharmaceutical, Agricultural, Animal and Microbial Biotechnologies.

Computational tools have become increasingly important in the processes leading to new inventions in Biotechnology. Computer Aided Drug Design (CADD) is a central part of the Rational approach for Drug Discovery. CADD is an inter-disciplinary field, which includes computational inputs from Chemistry, Biology, Pharmacology, Biotechnology and Information Technology etc. This is an emerging field with wide range of applications. It includes various aspects like Quantum Chemistry, Molecular Mechanics, Molecular Docking, Quantitative Structure Activity Relationship (3D QSAR), Conformational Analysis, etc. A major component of CADD is Molecular Modeling and Screening of the Protein ligand interactions. Our Endeavour is to create a lively environment for the advancement of Bioinformatics and to generate an innovative workforce in this exciting and expanding field.

Course Content
1.Biological Databases and Sequence Analysis : (Duration: 1 month)
  • Introduction to Bioinformatics
  • Molecular Databases
  • Primary Databanks, GENEBANK, EMBL, DDBJ
  • Secondary Databases, SWISSPORT, PIR, TrEMBL
  • PFAM. INTERPRO
  • Motif Database, PROSITE
  • Structural Database (PDB)
  • Classification Database(SCOP, CATH)
  • Eukaryotic Promoter Database
Sequence Analysis
  • Database similarity search
  • Pair wise alignment
  • Dot Matrix Comparison
  • Needleman-Wunsch Algorithm
  • Smith Waterman Algorithm
  • Local Sequence Alignment
  • Global Sequence Alignment
  • Multiple Sequence Alignment
  • Pattern, Motifs and Profiles
  • Primer Designing
2. Genomics And Proteomics > (Duration: 1 Month)Genomics
  • Sequence Alignments and its Applications
  • Genome Modelling
  • Gene Sequence analysis
  • Primer Designi
  • SNP Detection and Haplo typing
  • Chromosome Mapping and Linkage Analysis
  • Computational Assembly of a Genome
Proteomics
  • Protein Sequence Analysis
  • Approaches for Protein Structure Prediction
  • Phylogenetic analysis of Protein Families
  • Homology and comparative modeling of protein
  • Active site identification
3. Drug Designing And Drug Discovery (Duration: 1 Month)
Drug Designing
  • Building small molecules
  • Molecular Modelling
  • Properties of Drug molecules
  • Ligand- protein interactions
  • Binding Energy calculations
  • Energy minimization methods
  • Molecular Dynamics and simulation studies
  • Ligand based drug designing and Fragment based drug designing
CLINICAL RESEARCH:

Realizing the importance and significance of Clinical Research in the process of Discovering new Drugs and regimens in the treatment of diseases Global Institute of Biotechnology has established a Centre for Clinical and Translational Research called Global Centre for Clinical Research (GCCR). GCCR has taken an initiative to offer training programs in Clinical Research from Certificate to Doctoral ( Ph.D.) level , as an Authorized Study Center of Texila American University (TAU), Guyana, South America and Punjab Technical University , a leading State Government University, giving this new and exciting field a much deserving impetus and status both at global level and National level.

In addition GCCR has been engaged in training professionals in SAS (Statistics Analysis Systems) and Clinical Data Management (CDM), which have become gold standards for analysis and management of data in Clinical and Biological Research.

TRAINING NEEDS FOR CLINICAL RESEARCH

India is fast becoming a significant hub for conducting global clinical trials. This is evidenced by the three fold increment in clinical trial applications in last four years to the office of Drugs Controller General of India (DCGI).

According to McKinsey Report, the global clinical trial outsourcing to India in the pharmaceutical industry is estimated to reach around Rs 5,000 crores and there will be requirement of approximately 50,000 Clinical Research professionals.

Increasingly, a need is being felt for the development of institutes that may provide training and education in the clinical research segment and meet the growing demands Of skilled manpower by the industry.

The availability of qualified professionals who can skillfully plan, execute, monitor, and fully assess the dimensions of their work is an urgent necessity. The current output from the training institutes is unable to provide personnel for responsibilities across the hierarchy in clinical trial conduction.

The future Indian foray into clinical research will be highly dependent on the Indian ability to train high quality manpower.

COURSES OFFERED IN CLINICAL RESEARCH
TEXILA AMERICAN UNIVERSITY SCHOOL OF MEDICAL AND ALLIED HEALTH SCIENCES GUYANA, SOUTH AMERICA (LISTED BY WORLD HEALTH ORGANIZATION)
  1. PhD in Clinical and Translational Research (Duration 36 to 42 Months)
  2. M.Sc. Clinical Research (Duration: 18 Months ; 4 Trimesters)
PUNJAB TECHNICAL UNIVERSITY
(A State Governt University,Recognizmened by U.G.C.)
  1. M.Sc. Clinical Research (Duration: 4 Semesters : 2 Years)
  2. Advanced PG Diploma in Clinical Research(Duration 2 semesters ; 1 Year)
  3. PG Diploma in Clinical Research(Duration One Semester ; 6 Months)
GLOBAL CENTRE FOR CLINICAL RESEARCH (GCCR)
  1. PG Certificate Course in Statistical Analysis Systems (SAS) : (Duration: 8 Weeks)
  2. PG Certificate Course in Clinical Research and Regulatory Affairs (Duration: 8 Weeks )
  3. PG Certificate in Clinical Research and Clinical Data Management(Duration: 8 Weeks)
  4. PG Certificate Course in Clinical Research and Pharmacovigilance. (Duration 8 Weeks)
  5. PG Certificate Course in Clinical Research and GCP/GLP / ICH (Duration: 8 Weeks)
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